AJNN
Academic Journal of Neuropsychiatry and Neuropsychology

Academic Journal of Neuropsychiatry and Neuropsychology (formerly known as the Academic Journal of Neurology and Neurosurgery, e-ISSN:3023-6517), deals with neurology, neurosurgery, psychiatry and clinical psychology accepts articles on these topics. Academic Journal of Neuropsychiatry and Neuropsychology publishes original research articles, review articles, case reports, editorial commentaries, letters to the editor, educational articles, and conference/meeting announcements.

eISSN: 3108-8171
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Original Article
Examining the correlation of CRP, MPV and NLR levels with the severity of stroke in ischemic stroke patients
Abstract
Aims: The severity of ischemic stroke may vary depending on the values of some biochemical markers. We aimed to investigate the relationship between CRP, MPV and NLR levels and stroke severity in patients presenting to the emergency department with ischemic stroke.
Methods: 159 patients and 160 healthy volunteers who applied to the emergency department with a diagnosis of ischemic stroke were included in the study. CRP, NLR and MPV levels were measured in venous blood samples taken in the emergency department. The relationship between NHISS and CRP, MPV and NLR, which were measured at the time of admission to the emergency department, was examined.
Results: The average CRP value of individuals in the control group was 6.19 ± 6.48, and the average CRP value of individuals in the patient group was 16.79 ± 18.14. Sick individuals have higher CRP values. CRP values show statistically significant differences between patient and control groups (p<0.001). The average NLR value of individuals in the control group was determined as 2.50 ± 1.18, and the average NLR value of individuals in the patient group was determined as 5.74 ± 5.40. NLR values of sick individuals are higher. NLR values show statistically significant differences between patient and control groups (p<0.001). The average MPV value of individuals in the control group was 8.15 ± 0.84, and the average MPV value of individuals in the patient group was 8.57 ± 1.40. MPV values of sick individuals are higher. MPV values show statistically significant differences between patient and control groups (p=0.002).
Conclusion: Ischemic stroke severity varies depending on biochemical markers. More research is needed in terms of changes depending on many biochemical values.

Keywords : Ischemic stroke, NIHSS, CRP, MPV, NLR

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Article available in :
Volume 3, Issue 1, 2026
Page : 6-12
https://doi.org/10.51271/AJNN-0043
Article Information
Received : 26 Ara 2025
Accepted : 04 Mar 2026
Published : 29 Mar 2026
Corresponding Author :

Edip Varan: Department of Neurology, Beypazarı State Hospital, Ankara, Turkiye

[email protected]
Citation : Varan E, Baraklı S, Ateş Malone S, Bektaş H. Examining the correlation of CRP, MPV, and NLR levels with the severity of stroke in ischemic stroke patients. Acad J Neuropsychiatry Neuropsychol. 2026;3(1):6-12. doi:10.51271/AJNN-0043

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