AJNN
Academic Journal of Neurology and Neurosurgery

The Academic Journal of Neurology and Neurosurgery deals with Neurology and Neurosurgery accepts articles on these topics. Academic Journal of Neurology and Neurosurgery publishes original research articles, review articles, case reports, editorial commentaries, letters to the editor, educational articles, and conference/meeting announcements.

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Case Report
Cardio-cerebral infarction after syncope: a case report
Abstract
Cardio-cerebral infarction (CCI) initially introduced by Omar et al. in 2010, pertains to the concurrent manifestation of acute ischemic stroke (AIS) and acute myocardial infarction (AMI). In this study, we presented a 50-year-old man who arrived at the emergency department (ED) with syncope 6 hours prior. Neurological examination revealed left nasolabial fold flattening and left hemiparesis. Computed Tomography (CT) brain scan showed no intracranial hemorrhage, while diffusion brain Magnetic Resonance Imaging (MRI) displayed restricted diffusion of the right centrum ovale in the periventricular space. Electrocardiogram (ECG) indicated subacute ST-segment elevation in V2-V4, which resulted in the diagnosis of CCI. Due to ST-elevated MI, he received aspirin, ticagrelor, and heparin before undergoing emergent coronary angiography. After multidisciplinary discussion, the patient was planned for Coronary Artery Bypass Graft (CABG) surgery. His acute ischemic stroke was medically managed with antiplatelet and anticoagulant therapy. CCI is a rare and high-mortality disease arising from the simultaneous occurrence of AIS and AMI. Due to its rarity, there's no consensus on its treatment. The treatment process for AIS is limited to the patient's suitability for thrombolytic and thrombectomy therapy. We advise using a hybrid angiography laboratory for AIS patients.

Keywords : Cardio-cerebral infarction, acute myocardial infarction, acute ischaemic stroke, syncope

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1. Desai R, Mondal A, Prasad A, et al. Concurrent cardio-cerebral infarctions in COVID-19: a systematic review of published case reports/series. Curr Probl Cardiol. 2023;48(10):18. doi:10.1016/j.cpcardiol.2023. 101814
2. Yeo LL, Andersson T, Yee KW, et al. Synchronous cardiocerebral infarction in the era of endovascular therapy: which to treat first? J Thromb Thrombolysis. 2017;44(1):104-111. doi:10.1007/s11239-017-1484-2
3. Chong CZ, Tan BY, Sia CH, et al. Simultaneous cardiocerebral infarctions: a five-year retrospective case series reviewing natural history. Singapore Med J. 2022;63(11):686-690. doi:10.11622/smedj. 2021043
4. Omar HR, Fathy A, Rashad R, Helal E. Concomitant acute right ventricular infarction and ischemic cerebrovascular stroke; possible explanations. Int Arch Med. 2010;26(1):3-25. doi:10.1186/1755-7682- 3-25
5. Kijpaisalratana N, Chutinet A, Suwanwela NC. Hyperacute simultaneous cardiocerebral infarction: rescuing the brain or the heart first? Front Neurol. 2017;8(1):664. doi:10.3389/fneur.2017.00664
6. Gianstefani S, Douiri A, Delithanasis I, et al. Incidence and predictors of early left ventricular thrombus after ST-elevation myocardial infarction in the contemporary era of primary percutaneous coronary intervention. Am J Cardiol. 2014;113(7):1111-1116. doi:10.1016/j.amjcard.2013.12.015
7. Erdem AB, Tumer M. De Winter wave with ST segment elevation equivalent with speech disorder; a case report. J Emerg Med Case Rep. 2022;13(1):19-21. doi:10.33706/jemcr.991552
Article available in :
Volume 2, Issue 1, 2025
Page : 13-15
https://doi.org/10.51271/AJNN-0024
Article Information
Received : 31 Eki 2024
Accepted : 27 Oca 2025
Published : 21 Mar 2025
Corresponding Author :

Şeyda Gedikaslan: Department of Emergency Medicine, Ankara Etlik City Hospital, Ankara, Turkiye

[email protected]
Citation : Gedikaslan Ş, Şahin T, Erdem AB. Cardio-cerebral infarction following syncope. Acad J Neurol Neurosurg. 2025;2(1):13-15.

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